Thyroid Comprehensive Profile 2 Test
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Thyroid gland is an endocrine gland that produces thyroid hormones which carry out various energy related functions in the body. Normal production of these hormones is of utmost importance for the smooth functioning of the body. TSH, T3 and T4 are the thyroid hormones produced by these glands. Thyroperoxidase (TPO) is an enzyme involved in thyroid hormone synthesis. Thyroid peroxidase antibodies (TPO) antibodies destroy cells of thyroid gland and cause hypothyroidism. Thyroid profile test are blood tests used to identify the thyroid hormone levels in the body. Thyroid comprehensive profile-2 is a panel that includes a group of 4 tests performed to assess the thyroid hormone levels in the blood.
Thyroid Comprehensive Profile is used to diagnose thyroid diseases and conditions.
Price : ₹ 1,680
Thyroid profile test is mainly used to test the thyroid gland functioning. The most common scenarios where testing is carried out include:
– Cases of suspected hypothyroidism which may present as fatigue, increased sensitivity to cold, constipation, dry skin, weight gain, muscle weakness, puffy face.
– Cases of suspected hyperthyroidism which may present as unintentional weight loss, rapid heart rate, arrhythmia, palpitation, increase appetite, nervousness, irritability.
– For diagnosis of autoimmune thyroid disorders.
The profile includes thyroid profile test that measure the levels of FT3,FT4,TSH,and TPO in the blood.
• Free T4: This hormone helps regulate the body’s metabolism.
• Free T3: This hormone helps regulate the body’s metabolism.
• Thyroid Peroxidase: It can indicate the presence of autoimmune thyroid diseases such as Hashimoto’s thyroiditis.
• TSH is a hormone made by the pituitary gland. It controls how much thyroid hormone is made.
Thyroid profile test requires a blood sample post exposure to the allergens. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.
High TSH & high FT3 and FT4 : Thyroxine replacement therapy; pituitary adenoma; drugs like heparin, amiodarone, beta blockers, steroids; neonates; resistance to thyroid hormones
High TSH & low FT3 and FT4: Autoimmune thyroiditis, thyroidectomy, post-radiation, iodine deficiency, thyroid infiltrating tumour/ amyloid
Low TSH & Low FT3 and FT4: Central hypothyroidism, non-thyroidal illness
If the results of the Thyroid Comprehensive Profile-2 come back as Present or Absent, this could indicate an autoimmune thyroid disorder.
Low TSH & High FT3 and FT4: Grave’s disease, toxic multinodular goitre, toxic adenoma, thyroiditis, drugs, hyperemesis gravidarum & hydatiform mole, congenital hyperthyroidism.
TPO: High values: suggestive of Hashimoto thyroiditis; these antibodies can also be seen in Grave’s disease.
To prepare for the Thyroid Comprehensive Profile-2, you should fast (no food or drink besides water) for 8–12 hours before the test.
