Pregascreen Quadruple Marker Reflex Test
Sample Type
Recommended for
Report
The Pregascreen Quadruple is a second-trimester blood test (Quadruple Marker Test) used as a screening tool to identify an increased risk for fetal chromosomal abnormalities like Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and neural tube defects. Primarily four hormones are measured (AFP, HCG, estriol & Inhibin-A) in the mother’s blood, thus it is known as the Quadruple Marker test. This test can be performed any time between 14 to 22.6 weeks of pregnancy. If the initial screening shows a higher risk, a more definitive diagnostic test like NIPT (Non-Invasive Prenatal Testing) or Karyotyping/FISH of amniotic fluid is done.
Price : ₹ 4,500
- The Serum Quadruple marker test is a screening tool used in pregnancy (second trimester) to assess the risk of fetal chromosomal abnormalities. It identifies pregnancies with a higher chance of having a baby with Down syndrome, Edwards syndrome, or neural tube defects.
- If the Quadruple marker test shows a higher-than-average risk, further confirmation is recommended for a more precise diagnosis.
- Confirmation provides peace of mind by clarifying the risk.
- It allows parents to make informed decisions about their pregnancy management if a chromosomal abnormality is confirmed.
As per ACOG all pregnant women should be offered a prenatal screening and diagnostic test.
This test measures four markers (AFP, HCG, estriol & Inhibin-A) in the maternal blood. NIPT or Karyotyping/FISH of amniotic fluid (any one) is used for confirmation of screen positives with consent.
This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.
