HBV Mutation Profile by PCR & Sanger Sequencing – Serum
Sample Type
Recommended for
Report
The HBV Mutation Profile by PCR and Sanger Sequencing is a comprehensive diagnostic test used to identify drug-resistant mutations in the hepatitis B virus (HBV). This test utilizes polymerase chain reaction (PCR) amplification followed by Sanger sequencing to analyze specific regions of the HBV genome associated with drug resistance.
By analyzing the HBV mutation profile, this test provides valuable information about the presence of mutations that can confer resistance to antiviral drugs commonly used in the treatment of chronic hepatitis B. It can identify specific genetic changes in the HBV DNA polymerase gene, which is the target of many antiviral medications.
The HBV Mutation Profile by PCR and Sanger Sequencing can detect a wide range of mutations associated with drug resistance, including those related to lamivudine, adefovir, entecavir, tenofovir, and other antiviral drugs.
Price : ₹ 11,550
This test measures the presence of drug-resistant mutations in the Hepatitis B Virus (HBV).
- To identify drug-resistant HBV mutations in people with chronic hepatitis B
- To evaluate treatment response in people with hepatitis B undergoing antiviral therapy
Your doctor might recommend this test if you have
- chronic Hepatitis B,
- symptoms of liver disease like jaundice, fatigue, and abdominal pain,
- history of Hepatitis B infection, or
- been exposed to someone with Hepatitis B virus.
An abnormal result indicates that there are some mutations present in the virus, which can make treatment difficult.
