Atherosclerosis Profile 2 Test
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Atherosclerosis is the deposition of fats/cholesterol in the blood vessels leading to formation of plaques. This blocks or clogs the blood vessel leading to impaired blood supply to the vital organs of the body. Blood vessels of the heart are most commonly affected leading to coronary artery disorders. Cardiovascular disease is the top cause of death for heart attacks and strokes, in asymptomatic people. Risk factors including age, smoking status, hypertension, diabetes, cholesterol, and HDL cholesterol are used by physicians to identify individuals likely to have an ischemic event & to evaluate cardiovascular risk. The test measures the various parameters that can lead to atherosclerosis or formation of plaques.
The Atherosclerosis Profile-2 test, also known as the Atherosclerosis Profile 2 Test, is a comprehensive diagnostic test offered by SimplyCare, a leading diagnostics centre in India. This test is designed to assess the risk of cardiovascular diseases, particularly atherosclerosis, by utilising state-of-the-art technologies to provide accurate and quality results. The Atherosclerosis Profile 2 Test test helps doctors identify individuals at risk of heart attacks, strokes, and other cardiovascular complications.
By evaluating various lipid profiles, blood glucose levels, and other markers, the Atherosclerosis Profile-2 test provides a detailed assessment of an individual’s cardiovascular health. This information is crucial for early detection and preventive measures, allowing physicians to develop personalised treatment plans and lifestyle recommendations.
Created by: Dr.Shibani R Medical Writer, Medical Affairs
Reasons for Undergoing the Atherosclerosis Profile 2 Test
There are several reasons why a doctor may recommend the Atherosclerosis Profile-2 test:
- To identify individuals at risk of cardiovascular diseases, such as heart attacks and strokes
- To evaluate cardiovascular risk factors including age, smoking status, hypertension, diabetes, and cholesterol levels
- To monitor and manage existing cardiovascular conditions
- To provide early detection and predictive insights into the development of atherosclerosis, which is the deposition of fats and cholesterol in blood vessels leading to plaque formation
List of Parameters Considered During the Atherosclerosis Profile 2 Test
The Atherosclerosis Profile-2 test measures several parameters related to cardiovascular health:
- Lipid Profile: This includes total cholesterol, HDL (high-density lipoprotein) cholesterol, LDL (low-density lipoprotein) cholesterol, and triglycerides. High levels of LDL cholesterol and triglycerides and low levels of HDL cholesterol indicate a higher risk of atherosclerosis.
- Blood Glucose: To assess the presence of diabetes or prediabetes, which is a risk factor for cardiovascular disease.
- Blood Pressure: Hypertension is a significant risk factor for cardiovascular diseases.
- Other Risk Markers: Such as C-Reactive Protein (CRP), which indicates inflammation in the body, and homocysteine levels, which are linked to cardiovascular risk when elevated.
- Complete Blood Count (CBC) and other related tests may also be included to provide a comprehensive overview of the individual’s health status.
Atherosclerosis Profile 2 Test Preparation
Proper preparation is essential to ensure accurate results from the Atherosclerosis Profile-2 test. Here are the steps to follow:
- Fasting: It is usually recommended to fast for 8–12 hours before the test to ensure accurate lipid profile results. This means avoiding food and drinks (except water) during this period.
- Hydration: Drink plenty of water to ensure adequate blood volume and to make it easier for the phlebotomist to draw blood.
- Avoiding Heavy Meals and Alcohol: Refrain from consuming heavy meals and alcohol 24 hours prior to the test, as these can affect the accuracy of the results.
- Informing Your Doctor: Let your doctor know about any medications you are taking, as some may need to be temporarily stopped before the test to avoid interference with the results.
Atherosclerosis Profile 2 Test Results & Interpretation
The results of the Atherosclerosis Profile-2 test are interpreted based on the measured parameters:
- Normal Levels: Each parameter has a normal range. For example, total cholesterol should be below 200 mg/dL, LDL cholesterol below 100 mg/dL, and HDL cholesterol above 60 mg/dL.
- Abnormal Levels: Elevated levels of total cholesterol, triglycerides, and LDL cholesterol, or low levels of HDL cholesterol, can indicate an increased risk of atherosclerosis and cardiovascular diseases.
- Risk Assessment: The test results are used to calculate an individual’s overall cardiovascular risk, guiding further diagnostic tests or treatment plans if necessary.
- Consultation with a Doctor: Patients should discuss their Atherosclerosis Profile-2 test results with a qualified doctor to fully understand the implications and any necessary actions or lifestyle modifications.
Home Collection for Atherosclerosis Profile 2 Test Near You
SimplyCare offers the convenience of home sample collection for the Atherosclerosis Profile-2 test, ensuring a comfortable and safe experience for patients. A trained phlebotomist will visit your home to collect the required blood samples, maintaining the highest standards of sample handling and testing accuracy. This service eliminates the need to visit a diagnostic centre, saving time and effort while still providing reliable results. With timely and accurate reports, you can take proactive steps to manage your cardiovascular health. SimplyCare’s commitment to making healthcare accessible is evident in their efforts to provide quality diagnostic solutions conveniently at your doorstep.
Price : ₹ 5800
Atherosclerosis test is basically done to assess the status of the blood vessels of the heart and the risk of cardiac diseases, stroke, and peripheral vascular diseases. The cholesterol tests measure the levels of individual cholesterols in the blood. Lp (a) serum test is prescribed to understand how well the cholesterol is transported in the body. This gives a more detailed idea of the risk of heart diseases than the routine cholesterol screening and may help in early detection of potential cardiovascular problem. Apolipoproteins B/A is a test that can help predict cardiovascular risk in patients. It gives a more detailed idea of the risk of heart diseases than the routine cholesterol screening. Lp-pla2: It is a vascular-specific inflammatory biomarker providing information on risk for atherosclerotic cardiovascular disease (CVD). It is useful in cases of early stage heart diseases, family history of hypercholesterolemia and blood vessel diseases having normal triglycerides and total cholesterol levels. Homocysteine: Homocysteine is a type of amino acid used to make proteins. Vitamin B12, vitamin B6, and folic acid helps to break down homocysteine and change it into other substances your body needs. Abnormal homocysteine levels increase the predisposition to heart diseases. HsCRP: C Reactive Protein is an acute phase reactant in inflammation. High-sensitivity CRP is a useful test for determining risk of CVD, heart attacks, and strokes and evaluating a person before development of one of these health problems.
The test measures the Cholesterol-Total, HDL, Non HDL, LDL, VLDL and Triglycerides, Lp(a), Apolipoproteins B/A1, Lp-PLA2, HsCRP, Homocysteine levels in the blood.
The cholesterol tests measure the levels of individual cholesterols in the blood.
Lp (a) serum test analyzes how well the cholesterol is transported in the body.
Apolipoproteins B/A is a test. It predicts cardiovascular risk in patients. It gives a more detailed idea of the risk of heart disease.
Lp-pla2 is a vascular-specific inflammatory biomarker. It provides information on the risk of atherosclerotic cardiovascular disease (CVD).
Homocysteine is a form of amino acid. Abnormal homocysteine levels point out a predisposition to heart diseases.
HsCRP: High-sensitivity CRP is a great test for diagnosing the risk of developing CVD, heart attacks, and strokes.
This test requires a blood sample. A tourniquet (elastic) band is placed tightly on the upper arm. The patient is then asked to make a fist. This helps in the build-up of blood filling the veins. The skin is disinfected before needle insertion and the blood sample is collected in vacutainer.
During the test, a small sample of blood will be taken from your arm via a vein. The sample will then be sent to a laboratory for analysis.
You may experience minor discomfort during the blood draw. However, this should go away quickly. Once the procedure is over, you can resume your normal activities.
Maintaining lipid levels within the desirable ranges helps lower risk of heart attacks and stroke. Low HDL levels (below acceptable levels) are associated with increased risk for Atherosclerotic Cardiovascular disease (ASCVD) . High levels of Non HDL Cholesterol (above acceptable levels) are associated with increased risk for Atherosclerotic Cardiovascular disease (ASCVD). High lipoprotein (a) levels lead to cholesterol being deposited in the arterial walls which causes thickening or clogging of the arterial walls also known as “”atherosclerosis””. This disrupts the flow of blood to the heart and other vital organs. This increases the risk of heart diseases, strokes, and other peripheral arterial diseases. High B/A1 ratio increases the risk of heart diseases. Low ratio may reduce the risk of cardiac diseases and stroke. Apo-B/A1 ratio is a more specific test that gives a clearer picture of the risk of heart diseases as compared to routine cholesterol tests. High Lp- PLA2 levels may indicate need for more aggressive lipid lowering therapy to reduce the risk of CVD events. Patient with high levels are prone to rupture of plaque and associated cardiovascular events Low levels may mean that Lp- PLA2 levels are not contributing to the heart disease. High Homocysteine levels is also an important marker for risk assessment of coronary artery disease. High HsCRP is a sensitive predictor of increased cardiovascular risk in both men and women. It is used for assessment of risk of developing Myocardial infarction in patients presenting with Acute coronary syndrome. It also assesses risk of developing Cardiovascular disease or ischemic event in individuals who do not manifest disease at present.
Before the test, the patient might be asked to fast for 12 to 14 hours for optimal results.
Cholesterol- Total: Less than 200 mg/dL.
HDL: 40 mg/dL or higher
Non-HDL: Within 130 mg/DL
LDL: Less than 130 mg/dL.
VLDL: Anywhere in the range of 2 to 30 mg/DL
Triglycerides: Below 150 mg/dL for adults.
Lp (a): Within 30 mg/DL
Apolipoproteins B: Within 100 mg/DL
Apolipoproteins A1 Men:: 110 to 180 mg/DL
Apolipoproteins A1 Women: 110 to 205 mg/DL
Lp-PLA2: Less than 160 ng/mL.
HsCRP: Less than 3 mg/L.
Homocysteine: Between 5 and 15 micromol/L.
